Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model

Table 4 Genes that were not expected to be expressed in stria vascularis.

			Slc26a4 ^+/+		Slc26a4 ^-/-
No.	Gene	Description	Intensity	P	Intensity	P	Fold	Direction
1	Pres	Prestin	53	0/3	8	0/3
2	Kcnq4	K⁺ channel	160	0/6	160	0/6
3	Atp2b2	PMCA2	35	0/9	116	3/9
4	Calb1	Calbinin 28K	53	0/12	36	0/12
5	Calb2	Calretinin	28	0/3	27	0/3
6	Ache	Acetylcholinesterase	57	0/3	5	0/3
7	Slc1a3	Glutamate transporter GLAST	122	3/18	154	8/18
8	Gria1	Glutamate receptor, ionotropic	57	0/9	55	0/9
9	Atp6v1b1	H⁺ ATPase	58	0/3	26	0/3
10	Tecta	Tectorin, alpha	62	0/3	52	0/3
11	Tectb	Tectorin, beta	90	0/3	01	0/3
12	Otog	Otogelin	230	0/3	63	0/3
13	Otof	Otoferlin	231	0/3	214	0/3
14	Otop1	Otopetrin 1	54	0/3	62	1/3
15	Otop2	Otopetrin 2	247	0/3	203	0/3
16	Otop3	Otopetrin 3	60	0/3	47	0/3
17	Otos	Otospiralin	636	3/3	2,368	3/3	3.73	up
18	Slc4a7	Na⁺/HCO₃ ^- cotransporter	398	3/3	444	3/3	1.11
19	Kcnj16	K⁺ channel	280	2/6	239	1/6

Genes that are expected to be expressed in the organ of Corti, the modiolus or the vestibular labyrinth but not in stria vascularis (1–16), and genes that are expected to be expressed in spiral ligament but not in stria vascularis (17–19) are listed. For parameters 'P', 'Fold' and 'Direction', see the Gene array section in Methods. Fold changes are given when a gene was called Present (P) in Slc26a4 ^+/- or Slc26a4 ^-/- samples in at least half of the available probes. The direction of the fold change is only given when it exceeded 1.30. Fold changes lower than 1.30 were not considered significant.

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