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Table 3 CRABP1 was not differentially expressed in consequence of C99-overexpression in contrast to neurofilaments

From: Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Aβ42reduces their differentiation potential

Name

Fold change C99WT/mock

P-value

 

Transcriptomics

Proteomics

Transcriptomics

Proteomics

CRABP1

1.0

1.4

0.979

0.042

NEF3

-3.4

-1.8

0.024

0.086

NEFL

-3.0

-1.3

0.039

0.11

INA

-1.9

-1.3

0.069

0.029

  1. Comparison between C99WT and mock-transfected cells revealed effects mediated by C99. Neurofilament 3 (NEF3), neurofilament light polypeptide 68 kDa (NEFL) and internexin neuronal intermediate filament protein alpha (INA) were down-regulated as a consequence of C99-overexpression. CRABP1 was not differentially expressed (cut-off for differential expression at least 1.9 on the transcript or protein level, respectively).
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BMC Medicine

ISSN: 1741-7015

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