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Table 1 Subgroup analysis of antibiotic resistance rate (95% CI) by time periods

From: Global prevalence of Helicobacter pylori antibiotic resistance among children in the world health organization regions between 2000 and 2023: a systematic review and meta-analysis

Time period

AMX

MTZ

TET

CLA

LEV

MTZ + CLA

2000–2005

1.1 (0.5–2.2)

25.0 (16.4–36.3)

2.0 (1.5–2.7)

20.4 (12.1–32.3)

NA

8.5 (3.1–20.9)

2006–2010

6.7 (1.1–32.1)

35.7 (18.6–57.4)

2.5 (1.3–4.5)

27.7 (17.7–40.4)

NA

10.2 (0.6–16.8)

2011–2015

3.7 (1.5–9.1)

32.7 (19.2–49.9)

2.0 (0.2–17.0)

29.2 (21.0–38.9)

NA

15.0 (5.2–36.1)

2016–2020

2.7 (0.9–8.0)

33.5 (22.7–46.4)

2.4 (1.2–4.8)

27.7 (21.7–34.7)

7.2 (4.6–11.0)

13.3 (9.8–17.8)

2020–2023

16.1 (7.0–32.6)

38.5 (23.2–56.3)

2.7 (1.1–6.5)

49.5 (36.3–62.7)

23.4 (15.6–33.6)

23.8 (13.6–38.2)

  1. NA no data available, AMX amoxicillin, MTZ metronidazole, TET tetracycline, CLA clarithromycin, LEV levofloxacin