Table 2 Characteristics of the identified studies on cardiomyocyte proliferation between infarct border zone and remote zone in post-MI hearts
Study | Years | Country | n | Strains | Age | Time-points for outcome measures | Outcome measures |
|---|---|---|---|---|---|---|---|
Boogerd CJ et al. [31] | 2023 | Netherlands | 8 | C57BL/6 J | 9 w | 7 days post-MI | BrdU/EdU |
D’Uva G et al. [32] | 2015 | Israel | 6 | C57BL/6 J | 6 w | 21 days post-MI | Ki67; Aurora B |
Fan Y et al. [33] | 2020 | China | 3–5 | C57BL/6 J | 8 w | 14 days post-MI | Ki67; PH3; BrdU/EdU; Aurora B |
Fang W et al. [34] | 2019 | China | 10 | C57BL/6 J | Adult | 7 days post-MI | Ki67 |
Hirose K et al. [35] | 2019 | USA | 4 | C57BL/6 J | 6–13 w | 10 days post-MI | Ki67 |
Ma WY et al. [36] | 2020 | China | 5 | C57BL/6 J | 6–8 w | 14 days post-MI | PH3; Aurora B |
Malliaras K et al. [37] | 2013 | USA | 5 | MerCreMer/ZEG | 6–8 w | 35 days post-MI | BrdU/EdU |
Wang WE et al. [38] | 2017 | China | 8 | C57BL/6 J | 16 w | 21 days post-MI | BrdU/EdU |
Wang X et al. [6] | 2022 | USA | 6 | C57BL/6 J | 10–14 w | 14 days post-MI | Ki67; PH3; BrdU/EdU |
Wang X et al. [6] | 2022 | USA | 5 | C57BL/6 J | 10–14 w | 28 days post-MI | Ki67; PH3; BrdU/EdU |
Wang X et al. [39] | 2023 | China | 6 | C57BL/6 J | 10–12 w | 10 days post-MI | Ki67; PH3; BrdU/EdU |
Wang X et al. [39] | 2023 | China | 6–10 | C57BL/6 J | 10–12 w | 28 days post-MI | Ki67; PH3; BrdU/EdU |
Xie Y et al. [26] | 2014 | USA | 7 | C57BL/6 J | 8 w | 7 days post-MI | Ki67 |