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Fig. 8 | BMC Medicine

Fig. 8

From: Promising new drugs and therapeutic approaches for treatment of ovarian cancer—targeting the hallmarks of cancer

Fig. 8

Further hallmarks to target. The hallmarks deregulating cellular metabolism, unlocking phenotypic plasticity and the enabling characteristics tumor-promoting inflammation offer broad possibilities of altered pathways to target by cancer treatment. Auspicious targets are displayed in the boxes. CSC, cancer stem cells; CAF, cancer-associated fibroblasts; TCA, tricarboxylic acid cycle; TERT, telomerase reverse transcriptase; HMT, histone methylases; HDMS, histone demethylases; HAT, histone acetyltransferases; HDAC, histone deacetylase; DNMT, DNA methyltransferase. This figure was created using Biorender.com

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