Fig. 3

12-month progression-free survival (absence of disease progression or death at the 12-month time point) Kaplan-Meier graph. The 1-year hazard ratio (HR) and p value are from a Cox regression with the composite score (disease progression or death) as the outcome variable. Tick marks on the survival curves represent censoring events (time points where at least one patient was lost to follow-up). A loss-to-follow-up occurred if the patient’s last visit was before 12 months. The drop in the graph at 12 months is due to patients still in a state of disease progression at the 12-month time point (a small amount of jitter was added so the lines are distinguishable at the 12-month time point)