Fig. 5

Index-1, CA19-9, and miRNAs of Index-1 in groups of cT. Healthy control (HC, black) and pancreatic/biliary tract cancer (PBCa, red) distributions are shown according to the UICC for International Cancer Control clinical T classification. Circle spots represent each case, boxes represent the interquartile range (IQR), and whiskers represent 1.5 × IQR from the hinge. The blue dotted lines in Index-1 and logCA19-9 indicate the thresholds. The p-value was calculated using Students’ t-test, either linearly (Index-1, CA19-9) or using log base of 2 (miRNAs), as shown in each graph. PBca, pancreatic or biliary tract cancer; HC, healthy control; logCA19-9: CA19-9 (U/mL) in logarithm with base 10. cT1 ~ cT4: UICC clinical T classification