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Fig. 4 | BMC Medicine

Fig. 4

From: Investigating intestinal epithelium metabolic dysfunction in celiac disease using personalized genome-scale models

Fig. 4

Drugs targeting genes linked to altered sIECs metabolic tasks in CeD. Existing FDA-approved drugs that target 10 genes encoding six differentially active metabolic tasks in sIECs, which contribute to CeD development or symptoms, or reactions fully coupled to them, are shown. Lines represent gene-to-reaction links or gene-drug interactions. All drugs shown suppress the expression of the genes linked to them. The full list of all identified drugs (including those that are not FDA-approved) can be found in Additional File 1

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BMC Medicine

ISSN: 1741-7015

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