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Table 1 Demographic characteristics of patients with psoriasis and non-psoriasis individuals

From: Psoriasis increases the risk of Sjögren’s syndrome: evidence from a propensity score-matched cohort study and transcriptomic analysis

 

Before PSM matching

  

After PSM matching

  
 

Psoriasis N = 293,905

Non-psoriasis N = 10,089,569

p

SMD

Psoriasis N = 293,905

Non-psoriasis N = 293,905

p

SMD

Age, Mean ± SD

51.44 ± 15.33

47.60 ± 17.03

 < 0.001

0.237

51.44 ± 15.33

51.45 ± 15.33

0.873

 < 0.001

Sex (%)

 Female

154,802 (52.67)

5,420,180 (53.72)

 < 0.001

0.021

154,802 (52.67)

154,834 (52.68)

0.933

 < 0.001

 Male

124,661 (42.42)

4,088,503 (40.52)

 < 0.001

0.038

124,661 (42.42)

122,836 (41.79)

 < 0.001

0.013

 Unknown gender

14,442 (4.91)

580,886 (5.76)

 < 0.001

0.038

14,442 (4.91)

16,235 (5.52)

 < 0.001

0.027

Race (%)

 White

223,044 (75.89)

6,342,879 (62.87)

 < 0.001

0.285

223,044 (75.89)

223,066 (75.90)

0.947

 < 0.001

 Black or African American

14,406 (4.90)

1,286,954 (12.76)

 < 0.001

0.280

14,406 (4.90)

14,386 (4.90)

0.904

 < 0.001

 Asian

8861 (3.02)

404,728 (4.01)

 < 0.001

0.054

8861 (3.02)

9052 (3.08)

0.147

0.004

 Other/ unknown race

47,594 (16.19)

2,055,008 (20.37)

 < 0.001

0.054

47,594 (16.19)

47,401 (16.13)

0.147

0.004

BMI (%)

  < 18.5

2052 (0.70)

92,154 (0.91)

 < 0.001

0.024

2052 (0.70)

3027 (1.03)

 < 0.001

0.036

 18.5–24.9

23,573 (8.02)

992,430 (9.84)

 < 0.001

0.064

23,573 (8.02)

32,437 (11.04)

 < 0.001

0.103

 25–29.9

34,943 (11.89)

1,222,169 (12.11)

 < 0.001

0.007

34,943 (11.89)

42,383 (14.42)

 < 0.001

0.075

  ≥ 30

53,895 (18.34)

1,469,180 (14.56)

 < 0.001

0.102

53,895 (18.34)

50,842 (17.30)

 < 0.001

0.027

 Mean ± SD

31.16 ± 7.79

29.55 ± 7.23

 < 0.001

0.214

31.16 ± 7.79

29.68 ± 7.19

 < 0.001

0.197

Persons with potential health hazards related to socioeconomic and psychosocial circumstances (%)

1465 (0.50)

68,139 (0.68)

 < 0.001

0.023

1465 (0.50)

1461 (0.50)

0.941

 < 0.001

Tobacco use (%)

3019 (1.03)

100,539 (1.00)

0.098

0.003

3019 (1.03)

3698 (1.26)

 < 0.001

0.022

Personal history of nicotine dependence (%)

8998 (3.06)

259,049 (2.57)

 < 0.001

0.030

8998 (3.06)

9759 (3.32)

 < 0.001

0.015

Medical utilization (%)

 Ambulatory

178,828 (60.85)

5,434,826 (53.87)

 < 0.001

0.141

178,828 (60.85)

178,853 (60.85)

0.947

 < 0.001

 Emergency

26,089 (8.88)

820,941 (8.14)

 < 0.001

0.027

26,089 (8.88)

26,155 (8.90)

0.762

0.001

 Inpatient Encounter

17,075 (5.81)

557,968 (5.53)

 < 0.001

0.012

17,075 (5.81)

19,672 (6.69)

 < 0.001

0.037

Comorbidities (%)

 Nicotine dependence

12,610 (4.29)

332,724 (3.30)

 < 0.001

0.052

12,610 (4.29)

11,841 (4.03)

 < 0.001

0.013

 Alcohol related disorders

3608 (1.23)

91,069 (0.90)

 < 0.001

0.032

3608 (1.23)

3097 (1.05)

 < 0.001

0.016

 Hypertensive diseases

55,293 (18.81)

1,686,276 (16.71)

 < 0.001

0.055

55,293 (18.81)

55,293 (18.81)

1.000

 < 0.001

 Disorders of lipoprotein metabolism and other lipidemias

46,482 (15.82)

1,389,264 (13.77)

 < 0.001

0.058

46,482 (15.82)

49,502 (16.84)

 < 0.001

0.028

 Diabetes mellitus

26,074 (8.87)

720,216 (7.14)

 < 0.001

0.064

26,074 (8.87)

26,048 (8.86)

0.905

 < 0.001

 Depressive episode

16,394 (5.58)

466,098 (4.62)

 < 0.001

0.044

16,394 (5.58)

16,514 (5.62)

0.496

0.002

 Ischemic heart diseases

12,807 (4.36)

369,715 (3.66)

 < 0.001

0.035

12,807 (4.36)

12,844 (4.37)

0.813

0.001

 Diseases of liver

8139 (2.77)

169,911 (1.68)

 < 0.001

0.074

8139 (2.77)

6573 (2.24)

 < 0.001

0.034

 Cerebrovascular diseases

5167 (1.76)

170,743 (1.69)

0.006

0.005

5167 (1.76)

5798 (1.97)

 < 0.001

0.016

 Rheumatoid arthritis with rheumatoid factor

1164 (0.40)

14,519 (0.14)

 < 0.001

0.049

1164 (0.40)

1401 (0.48)

 < 0.001

0.012

 Other rheumatoid arthritis

7287 (2.48)

53,389 (0.53)

 < 0.001

0.161

7287 (2.48)

7249 (2.47)

0.750

0.001

 Wegener's granulomatosis

86 (0.03)

1423 (0.01)

 < 0.001

0.010

86 (0.03)

68 (0.02)

0.147

0.004

 Microscopic polyangiitis

11 (0.00)

200 (0.00)

0.037

0.003

11 (0.00)

10 (0.00)

0.827

0.001

 Systemic lupus erythematosus

1127 (0.38)

19,037 (0.19)

 < 0.001

0.036

1127 (0.38)

778 (0.27)

 < 0.001

0.021

 Dermatopolymyositis

191 (0.07)

2862 (0.03)

 < 0.001

0.017

191 (0.07)

128 (0.04)

 < 0.001

0.009

 Systemic sclerosis

189 (0.06)

4019 (0.04)

 < 0.001

0.011

189 (0.06)

164 (0.06)

0.183

0.003

Medications (%)

 Hormones/synthetics/modifiers

88,842 (30.23)

2,147,353 (21.28)

 < 0.001

0.206

88,842 (30.23)

88,861 (30.24)

0.957

 < 0.001

 Antirheumatics

45,866 (15.61)

1,043,371 (10.34)

 < 0.001

0.157

45,866 (15.61)

37,623 (12.80)

 < 0.001

0.080

  1. BMI body mass index, PSM propensity score matching, SMD standardized mean difference
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BMC Medicine

ISSN: 1741-7015

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