Beyond LDL cholesterol: remnant cholesterol is associated with cardiometabolic risk factors in children

Table 3 Beta coefficient (95% confidence interval) of cardiometabolic risk factors for continuous z-score of remnant cholesterol levels obtained in multilevel mixed-effects generalized linear regression models according to LDL-c level (low vs. high) adjusted by age, sex, and HDL-c

Models	Cardiometabolic risk factors
Models	Insulin	HOMA-IR	MAP	WC	CRF
Low LDL-c (< 110 mm/dL)
Z-score of RC	2.305 (2.097, 2.512)**	0.499 (0.452, 0.545)**	1.397 (1.050, 1.743)**	2.842 (2.299, 3.384)**	− 0.367 (− 0.471, − 0.263)**
High LDL-c (≥ 110 mg/dL)
Z-score of RC	1.573 (1.255, 1.891)**	0.347 (0.276, 0.418)**	0.749 (0.239, 1.259)**	3.133 (2.450, 3.816)**	− 0.284 (− 0.411, − 0.156)**

CRF, cardiorespiratory fitness, HDL-c high-density lipoprotein cholesterol, HOMA-IR homeostatic model assessment for insulin resistance, LDL-c low-density lipoprotein cholesterol, MAP mean arterial pressure, RC remnant cholesterol, WC waist circumference
^**p-value < 0.001

ISSN: 1741-7015