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Table 2 Association between geographical, meteorological factors and socio-demographic factors with RSV season onset and offset

From: Understanding the local-level variations in seasonality of human respiratory syncytial virus infection: a systematic analysis

Region

Best model

Difference in RSV onset

Difference in RSV offset

Nationwide, Spain

Variables

Temperature (per 1 °C)

Relative humidity (per 5%)

Population size <5 years old (per 10,000 people)

Annual household income (per 1000 euro)

Longitude (per 1°)

Temperature (per 1 °C)

Estimate

− 4.73 days

0.54 days

1.99 days

− 4.77 days

− 2.76 days

19.33 days

95% CI

[− 5.66, − 3.81]

[0.18, 0.90]

[1.15, 2.82]

[− 6.43, − 3.12]

[− 4.14, − 1.38]

[6.21, 32.44]

Adjusted 95% CI

[− 7.79, − 1.68]

[0.11, 0.96]

[0.44, 3.54]

[− 8.42, − 1.13]

[− 4.95, − 0.57]

[3.99, 34.67]

Adjusted R2

0.84

0.49

AIC

362.83

349.00

Nationwide, Japan

Variables

Latitude (per 1°)

Temperature (per 1 °C)

Relative humidity (per 5%)

Population size <5 years old (per 10,000 people)

Annual household income (per 1000 euro)

Longitude (per 1°)

Latitude (per 1°)

Temperature (per 1 °C)

Estimate

− 4.49 days

− 5.76 days

− 0.40 days

− 0.73 days

1.79 days

− 3.66 days

7.61 days

9.23 days

95% CI

[− 6.07, − 2.90]

[− 6.19, − 5.33]

[− 0.60, − 0.20]

[− 1.13, − 0.33]

[0.73, 2.85]

[− 5.41, − 1.92]

[4.91, 10.31]

[1.92, 16.65]

Adjusted 95% CI

[− 8.54, − 0.44]

[− 7.57, − 3.95]

[− 0.76, − 0.05]

[− 1.36, − 0.10]

[0.26, 3.32]

[− 6.87, − 0.45]

[0.74, 14.48]

[1.64, 16.83]

Adjusted R2

0.75

0.35

AIC

2249.05

2548.23

Scotland, UK

Variables

Temperature (per 1 °C)

Wind speed (per 1m/s)

Temperature (per 1 °C)

Relative humidity (per 5%)

Estimate

− 6.25 days

2.77 days

5.48 days

− 0.62 days

95% CI

[− 7.16, − 5.34]

[0.86, 4.67]

[4.19, 6.77]

[− 1.08, − 0.16]

Adjusted 95% CI

[− 10.49, − 2.55]

[0.49, 5.04]

[1.04, 9.93]

[− 1.13, − 0.11]

Adjusted R2

0.66

0.46

AIC

810.06

804.08

  1. AIC Akaike Information Criterion, CI Confidence interval