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Fig. 1 | BMC Medicine

Fig. 1

From: Visceral adipose tissue area and proportion provide distinct reflections of cardiometabolic outcomes in weight loss; pooled analysis of MRI-assessed CENTRAL and DIRECT PLUS dietary randomized controlled trials

Fig. 1

Abdominal adipose tissue area and proportion across various characteristics (baseline and 18-month changes). Heatmaps of Kendall’s tau partial correlations. A Baseline characteristics across abdominal adipose tissue sex-specific ranks, adjusted for age, weight, physical activity, and intervention trial (CENTRAL, DIRECT PLUS). SSAT area, n = 553; DSAT area, n = 560; VAT area, n = 564; VAT proportion, n = 533. B 18-month change characteristics across abdominal adipose tissue sex-specific ranks change, adjusted for age, weight loss, physical activity change, and intervention trial. Δ SAT area n = 430, Δ DSAT area n = 438, Δ VAT area n = 440, Δ VAT proportion n = 429. Correlations are color-coded with blue = positive correlation and red = negative correlation. Benjamini–Hochberg correction was used for multiple comparisons (FDR 5%). Asterisks (***, **, *) correspond to FDRs of 0.001, 0.01, and 0.05, respectively. Abbreviations: SSAT, superficial subcutaneous adipose tissue; DSAT, deep subcutaneous adipose tissue; VAT, visceral adipose tissue; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; HOMA-IR, homeostatic model assessment of insulin resistance; hsCRP, high-sensitivity C reactive protein; HDLc, high-density lipoprotein cholesterol; GGT, gamma-glutamyl transferase; ALKP, alkaline phosphatase; AST, aspartate transaminase; ALT, alanine transaminase

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BMC Medicine

ISSN: 1741-7015

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