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Table 2 The ovarian reserve and controlled ovarian hyperstimulation of HBsAg positive group and HBsAg negative group

From: Positive hepatitis B surface antigen leads to a decrease in ovarian reserve in infertile patients receiving first in vitro fertilization treatment

 

HBsAg+(n = 1574)

HBsAg(n = 1574)

P

No. of AFC

11 (7,16)

18 (14,20)

< 0.001

FSH (IU/L)

7.88 (6.49,9.5)

6.82 (5.81,8.1)

< 0.001

LH/FSH

0.5 (0.37,0.69)

0.63 (0.48,0.85)

< 0.001

AMH (ng/ml)

2.25 (1.18,3.66)

6.81 (5.56,8.24)

< 0.001

Duration of GN stimulation (days)

10 (9,12)

10 (9,11)

0.116

Total dose of GN used (IU)

1875 (1425,2325)

1600 (1300,2100)

< 0.001

No. of oocytes retrieved

7 (4,12)

14 (10,18)

< 0.001

No. of MII eggs

7 (3,11)

12 (8,16)

< 0.001

  1. AFC, antral follicle count; FSH, follicle-stimulating hormone; LH, luteinizing hormone; AMH, anti-mullerian hormone; Gn, gonadotropins; MII, mature