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Table 2 Plasma and lung tissue betamethasone concentration at delivery. No significant differences in fetal plasma betamethasone concentrations were identified between male vs. female (CS1 p = 0.74, CS2 p = 0.26) or ANS responder vs. non-responder (CS1 p = 0.58, CS2 p = 0.60) animals within either ANS treatment group

From: Single-nucleotide polymorphisms in dizygotic twin ovine fetuses are associated with discordant responses to antenatal steroid therapy

  

Mean

SD

Mean absolute difference between twins

Maternal plasma

CS1

 

14.8

11.4

-

CS2

 

7.8

2.2

-

Negative control group

 

 < 1

-

-

Fetal plasma

CS1

Total (n = 22)

2.5

1.5

0.22

 

Male

2.5

1.5

-

 

Female

2.5

1.5

-

 

Responder

2.4

1.3

-

 

Non-responder

2.7

1.7

-

CS2

Total (n = 20)

1.6

0.3

0.12

 

Male

1.7

0.4

-

 

Female

1.6

0.2

-

 

Responder

1.7

0.3

-

 

Non-responder

1.6

0.3

-

Fetal lung tissue

CS1

Total

42.6

19.4

6.9

 

Male

43.7

21.7

-

 

Female

41.0

16.6

-

 

Responder

40.1

15.2

-

 

Non-responder

45.6

24.0

-

CS2

Total

20.7

4.9

1.8

 

Male

23.0

4.5

-

 

Female

18.9

4.6

-

 

Responder

21.1

4.3

-

 

Non-responder

20.1

5.9

-