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Fig. 7 | BMC Medicine

Fig. 7

From: Helicobacter pylori SlyD stabilizes TPT1 via hnRNPK and enhances OCT1-mediated CDX2 transcriptional activation to drive gastric intestinal metaplasia

Fig. 7

H. pylori SlyD is related to the expression of hnRNPK, TPT1, OCT1, and CDX2 in the IM of human gastric mucosa. Representative images of hnRNPK/TPT1/OCT1/CDX2 IHC staining in GS and GIM, respectively (Magnification: ×100). B Comparison of semiquantitative scores of hnRNPK/TPT1/OCT1/CDX2 protein expression in GS (n=18) and GIM (n=52). C Comparison of semiquantitative scores of hnRNPK/TPT1/OCT1/CDX2 protein expression in H. pylori-negative (n=22) or H. pylori-positive (n=48) cases. Comparison of semiquantitative scores of hnRNPK/TPT1/OCT1/CDX2 protein expression in HpslyD-negative (n=19) or HpslyD-positive (n=29) cases. The scatter plots of hnRNPK and TPT1 expressions, OCT1 and TPT1 expressions, and OCT1 and CDX2 expressions, respectively in H. pylori-negative (n=14) or H. pylori-positive (n=38), and HpslyD-negative (n=13) or HpslyD-positive (n=25) cases. Significance Levels: *P< .05, **P< .01, ***P < .001, ns: non-significant

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