Table 1 Deaths, mortality rates, and EAPC of youths and young adults with HSBP (1990–2021)

Global

93664.47 (69113.95–118062.32)

127487.58 (97748.55–156978.59)

4.27 (3.15–5.39)

4.29 (3.29–5.28)

-0.12 (-0.21–0.03)

4.66 (3.36–6.00)

4.14 (3.10–5.16)

-0.47 (-3.33–2.47)

36.11 (20.96–52.37)

SDI region

 High SDI

9699.80 (7344.44–11964.32)

7118.79 (5406.72–8830.94)

2.80 (2.12–3.45)

2.02 (1.53–2.50)

-1.03 (-1.35–0.72)

2.61 (1.94–3.26)

1.73 (1.28–2.19)

-1.36 (-5.86–3.36)

-26.61 (-35.02–16.35)

 High-middle SDI

19746.37 (13960.11–25692.39)

17609.11 (12764.15–22793.32)

4.36 (3.08–5.68)

4.00 (2.90–5.18)

-0.85 (-1.10–0.60)

4.43 (2.98–6.04)

3.27 (2.15–4.42)

-1.14 (-5.69–3.62)

-10.82 (-27.93–13.52)

 Middle SDI

33157.55 (24080.04–41981.49)

42869.27 (32404.34–54638.33)

4.41 (3.20–5.58)

4.62 (3.49–5.89)

0.07 (-0.06–0.20)

5.08 (3.56–6.77)

4.26 (3.10–5.49)

-0.76 (-3.91–2.49)

29.29 (10.42–53.46)

 Low-middle SDI

23047.68 (16768.44–29193.77)

42291.92 (31604.77–52024.95)

5.08 (3.70–6.44)

5.27 (3.94–6.48)

0.20 (0.12–0.27)

5.97 (4.22–7.76)

5.57 (4.13–6.93)

-0.31 (-2.45–1.87)

83.50 (59.69–114.62)

 Low SDI

7903.50 (5755.03–9978.91)

17485.65 (13519.62–21571.99)

4.29 (3.12–5.41)

3.89 (3.01–4.80)

-0.32 (-0.40–0.24)

5.17 (3.64–6.68)

4.69 (3.52–5.89)

-0.35 (-1.58–0.89)

121.24 (88.04–158.41)

GBD region

 Andean Latin America

335.10 (205.17–490.57)

613.08 (384.51–842.76)

2.17 (1.33–3.17)

2.26 (1.42–3.11)

0.63 (0.18–1.08)

2.53 (1.27–4.25)

2.27 (1.33–3.38)

-0.58 (-4.14–3.10)

82.95 (26.87–179.57)

 Australasia

127.50 (90.75–165.12)

71.83 (47.12–99.18)

1.56 (1.11–2.03)

0.69 (0.45–0.95)

-3.40 (-3.78–3.02)

1.50 (1.04–1.98)

0.60 (0.35–0.88)

-2.70 (-8.38–3.33)

-43.67 (-57.95–29.22)

 Caribbean

634.64 (438.98–871.70)

1001.87 (702.43–1320.62)

4.27 (2.95–5.86)

5.50 (3.86–7.26)

1.17 (0.94–1.40)

4.97 (3.05–7.13)

5.42 (3.51–7.53)

0.29 (-0.69–1.27)

57.86 (20.49–115.45)

 Central Asia

1837.37 (1371.55–2315.41)

2049.46 (1562.06–2569.45)

6.46 (4.82–8.14)

5.48 (4.18–6.87)

-1.65 (-2.02–1.28)

7.16 (5.07–9.26)

5.02 (3.60–6.43)

-1.17 (-5.29–3.13)

11.54 (-7.12–34.31)

 Central Europe

3203.43 (2436.68–3912.58)

983.45 (772.09–1188.38)

6.84 (5.20–8.35)

2.81 (2.20–3.39)

-2.84 (-3.10–2.59)

6.15 (4.64–7.60)

2.27 (1.73–2.77)

-3.15 (-7.84–1.79)

-69.30 (-73.03–64.91)

 Central Latin America

1812.50 (1285.44–2344.67)

2893.40 (2019.25–3813.43)

2.66 (1.88–3.43)

2.86 (2.00–3.77)

0.29 (-0.17–0.76)

3.19 (2.05–4.30)

2.87 (1.88–4.02)

-0.51 (-4.05–3.17)

59.64 (22.20–106.95)

 Central Sub-Saharan Africa

895.21 (589.38–1206.66)

1783.27 (1157.30–2472.30)

4.31 (2.84–5.81)

3.30 (2.14–4.57)

-1.09 (-1.17–1.01)

5.31 (3.28–7.74)

3.96 (2.48–5.83)

-0.99 (-2.75–0.80)

99.20 (39.73–175.42)

 East Asia

17742.56 (10323.60–26971.71)

19429.98 (11228.35–28250.35)

3.14 (1.82–4.77)

4.06 (2.34–5.90)

0.45 (0.17–0.73)

3.42 (1.55–5.87)

3.28 (1.38–5.18)

-0.57 (-4.70–3.74)

9.51 (-33.42–79.82)

 Eastern Europe

6170.65 (4678.99–7494.41)

4589.38 (3466.21–5693.33)

7.19 (5.46–8.74)

6.94 (5.24–8.60)

-1.20 (-1.68–0.72)

6.32 (4.79–7.76)

5.16 (3.83–6.45)

-0.58 (-6.37–5.57)

-25.63 (-35.46–15.50)

 Eastern Sub-Saharan Africa

3068.94 (2100.94–3909.50)

6716.99 (5169.56–8367.89)

4.33 (2.96–5.51)

3.83 (2.95–4.78)

-0.45 (-0.53–0.37)

5.40 (3.65–7.12)

4.68 (3.45–5.99)

-0.52 (-2.01–0.99)

118.87 (80.53–173.91)

 High-income Asia Pacific

1811.90 (1324.09–2379.82)

495.61 (318.55–675.68)

2.68 (1.96–3.53)

0.98 (0.63–1.34)

-3.72 (-3.93–3.50)

2.65 (1.85–3.57)

0.82 (0.48–1.18)

-3.99 (-9.09–1.40)

-72.65 (-79.48–65.94)

 High-income North America

2325.68 (1684.25–2954.20)

2918.31 (2266.37–3534.42)

2.05 (1.49–2.61)

2.37 (1.84–2.87)

0.57 (0.29–0.85)

1.86 (1.30–2.41)

2.19 (1.62–2.79)

0.67 (-3.73–5.27)

25.48 (4.14–57.83)

 North Africa and Middle East

9395.09 (6635.86–12042.71)

14944.98 (10920.21–18877.18)

7.02 (4.96–9.00)

5.88 (4.29–7.42)

-0.41 (-0.57–0.26)

8.38 (5.71–11.04)

5.59 (3.99–7.28)

-1.38 (-3.02–0.29)

59.07 (31.99–95.44)

 Oceania

131.37 (82.19–194.21)

370.90 (221.34–558.02)

4.95 (3.09–7.31)

6.58 (3.93–9.90)

0.95 (0.76–1.14)

5.93 (3.49–9.26)

7.13 (3.77–11.65)

0.63 (-1.94–3.26)

182.33 (98.35–328.28)

 South Asia

19585.87 (13789.69–25280.66)

35684.28 (25527.26–45305.33)

4.54 (3.19–5.86)

4.51 (3.23–5.73)

-0.01 (-0.22–0.20)

5.21 (3.60–6.82)

4.69 (3.31–6.01)

-0.43 (-2.97–2.18)

82.19 (55.72–112.11)

 Southeast Asia

12358.98 (8924.82–16047.04)

19447.10 (14405.05–25081.66)

6.27 (4.53–8.15)

7.01 (5.19–9.04)

0.52 (0.40–0.65)

7.25 (5.08–9.55)

6.77 (4.92–8.84)

-0.37 (-3.02–2.34)

57.35 (32.73–90.74)

 Southern Latin America

504.06 (309.45–726.17)

429.48 (292.43–563.27)

2.64 (1.62–3.81)

1.66 (1.13–2.18)

-1.17 (-1.42–0.91)

2.77 (1.49–4.27)

1.59 (0.95–2.26)

-1.64 (-5.35–2.21)

-14.80 (-37.22–19.76)

 Southern Sub-Saharan Africa

1491.37 (1142.60–1860.14)

1759.06 (1350.80–2207.80)

6.90 (5.29–8.61)

5.17 (3.97–6.49)

-1.27 (-2.15–0.37)

8.38 (5.75–11.03)

5.02 (3.59–6.52)

-1.67 (-2.98–0.34)

17.95 (-7.79–51.10)

 Tropical Latin America

3775.90 (2826.36–4750.50)

2914.62 (2215.01–3617.20)

5.87 (4.39–7.39)

3.30 (2.51–4.10)

-2.01 (-2.25–1.77)

6.63 (4.68–8.54)

3.02 (2.24–3.77)

-2.55 (-5.32–0.30)

-22.81 (-32.32–11.13)

 Western Europe

3764.53 (2878.37–4597.13)

1020.63 (758.95–1260.87)

2.61 (2.00–3.19)

0.79 (0.58–0.97)

-4.06 (-4.19–3.93)

2.52 (1.93–3.10)

0.69 (0.50–0.87)

-4.19 (-8.78–0.63)

-72.89 (-75.54–69.77)

 Western Sub-Saharan Africa

2691.81 (2008.99–3452.58)

7369.89 (5349.01–9284.06)

3.76 (2.81–4.82)

3.85 (2.80–4.86)

0.22 (0.04–0.40)

4.58 (3.34–5.94)

4.71 (3.34–6.09)

0.03 (-1.66–1.76)

173.79 (117.37–253.76)