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Fig. 5 | BMC Medicine

Fig. 5

From: Cryoablation-induced modulation of Treg cells and the TGF-β pathway in lung adenocarcinoma: implications for increased antitumor immunity

Fig. 5

Cryoablation suppresses lung cancer cell proliferation in mouse models. A, B Tumor volume measurements in each group following cryoablation for 14 days, n = 5 mice per group. Statistical significance was assessed using one-way ANOVA. *P < 0.05, **P < 0.01. C HE staining results of tumor tissue 14 days post-cryoablation exposed changes in the Cry group, with cells appearing smaller and rounder, with condensed nuclei, dense chromatin, and displaying apoptotic morphology. D, E Cryoablation downregulated Ki-67 expression in lung cancer tissue. n = 3 mice per group. Statistical significance was assessed using one-way ANOVA. *P < 0.05, **P < 0.01

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BMC Medicine

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