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Table 1 Patient demographics and clinical data according to Definition I

From: Long-term outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention without standard modifiable cardiovascular risk factors: findings from the OPT-CAD cohort

 

SMuRFs-present

ACS (n = 5296)

SMuRFs-absent ACS (n = 392)

P-value

Age, years

59.68 ± 10.81

61.90 ± 11.07

 < 0.001

Male

4064 (76.74%)

235 (59.95%)

 < 0.001

BMI, kg/m2

24.61 ± 2.94

23.37 ± 3.13

 < 0.001

Family history of CAD

612 (11.56%)

20 (5.10%)

 < 0.001

Anemia

510 (9.79%)

48 (12.34%)

0.105

Type of CAD

-

-

0.022

 STEMI

1910 (36.06%)

167 (42.60%)

-

 NSTEMI

664(12.54%)

38(9.69%)

-

 UA

2722 (51.40%)

187 (47.70%)

-

Smoking

-

-

 < 0.001

None

2298 (43.39%)

392 (100.00%)

-

Current

2576 (48.64%)

0 (0.00%)

-

Former

422 (7.97%)

0 (0.00%)

-

eGFR, mL/min/1.73m2

112.91 ± 40.25

111.57 ± 35.42

0.477

TC, mmol/L

4.46 ± 1.21

4.49 ± 0.86

0.538

LDL-C, mmol/L

2.61 ± 1.04

2.60 ± 0.77

0.838

HDL-C, mmol/L

1.05 ± 0.34

1.30 ± 0.30

 < 0.001

LVEF, %

60.31 ± 8.72

60.06 ± 8.49

0.582

Medical therapy at discharge

 Aspirin

5228 (98.72%)

385 (98.21%)

0.401

 Clopidogrel

5208 (98.34%)

383 (97.70%)

0.349

 β-blocker

4048 (76.44%)

281 (71.68%)

0.033

 ACEI/ARB

3773 (71.24%)

211 (53.83%)

 < 0.001

 Statin

5116 (96.60%)

388 (98.98%)

0.010

 PPI

2039 (38.50%)

139 (35.46%)

0.232

  1. Data are presented as n (%) or mean ± SD
  2. SMuRFs standard modifiable cardiovascular risk factors, BMI body mass index, CAD coronary artery disease, STEMI ST-elevation myocardial infarction, NSTEMI non-ST-elevation myocardial infarction, UA unstable angina, TC total cholesterol, HDL high-density lipoprotein, LDL low-density lipoprotein, eGFR estimated glomerular filtration rate, LVEF left ventricular ejection fraction, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blockade, PPI proton pump inhibitor