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Table 4 Included study characteristics

From: Modifications to the National Early Warning Score 2: a Scoping Review

Author/year

Study type

Sample size

Population

Main outcome measures

Akel et al., 2021 [33]

Retrospective cohort

556,848

Medical-surgical admissions, 18 + 

ICU transfer within 24 h

Death within 24 h

Composite of ICU transfer and death within 24 h

Clarke et al., 2023 [34]

Retrospective cohort

3704

SARS-CoV-2 / influenza patients (viral respiratory infections)

Composite of cardiac arrest, ICU admission or death within 24 h

Forster et al., 2022 [35]

Retrospective cohort

7487 (derivation) + 8739 (validation)

Respiratory patients

Death within 24 h

Gonem et al., 2022 [36]

Retrospective cohort

1100

Respiratory patients

Composite of ICU admission or death within 24 h

Kabell Nissen et al., 2022 [42]

Prospective cohort

2183

Emergency department patients, 65 + 

Death within 30 days

Kamal et al., 2024 [37]

Retrospective cohort

219 (for predicting in-hospital mortality)

175 (for predicting serious illness development)

Sars-CoV-2 patients, 18 + 

Serious illness within 7 days

In-hospital mortality within 28 days

Malycha et al., 2019 [41]

Retrospective cohort

83,304

Hospital admissions, 18 + 

In-hospital death or unplanned intensive care admission within 24 h

Maves et al., 2021 [43]

Prospective cohort

184

Hospitalised adults with confirmed COVID-19 not requiring invasive mechanical ventilation at admission

Invasive ventilation or death during entire hospital stay

Nissen et al., 2022 [25]

Retrospective cohort

14,809 (development) + 50,448 (validation)

Emergency department patients, 18 + 

In-hospital mortality during entire hospital stay

ICU admission during entire hospital stay

Trongtrakul et al., 2024 [38]

Retrospective cohort

725

Sars-CoV-2 patients, 18 + 

Severe Covid 19 pneumonia

Yun et al., 2021 [39]

Retrospective cohort

41,687

Emergency department patients with suspected sepsis, 19 + 

Septic shock within 24 h

Zhu et al., 2020 [40]

Retrospective cohort

13,319

Postoperative adult cardiac patients

Composite of cardiac arrest, ICU admission or death within 24 h