Fig. 3

Perioperative blood levels of inflammatory markers. The data are presented as the median with a 95% confidence interval (CI) and were analyzed using two-way analysis of variance (ANOVA) (with Sidak’s multiple comparisons test when appropriate). A There was no significant difference in S100β levels between groups (F = 0.49, P = 0.483). B There was no significant difference in NSE levels between groups (F = 1.01, P = 0.318). C Postoperative CRP levels in the anti-inflammatory bundle group were significantly lower than those in the control group (predicted mean difference: − 29.4 [95% CI: − 46.5, − 12.2] mg·L.−1, adjusted P < 0.001)