Table 2 Outcomes and postoperative data
Outcomes | Anti-inflammatory bundle (n = 62) | Control group (n = 61) | Risk/median differencea [(95% CI), %] | Risk ratio (95% CI) | P value |
|---|---|---|---|---|---|
Primary outcome | |||||
 POD [n (%)] | 9 (14.5) | 27 (44.3) |  − 29.7 (− 45.0, − 14.5) | 0.33 (0.17, 0.64) | 0.001 |
Secondary outcomes | |||||
 Pain at rest (NRS) | 1.0 [1.0, 1.0] | 2.0 [1.0, 2.0] |  − 1.0 (− 1.0, − 0.5) | – |  < 0.001 |
 Pain on activity (NRS) | 3.0 [3.0, 4.0] | 4.0 [3.2, 4.0] |  − 1.0 (− 1.0, − 0.2) | – |  < 0.001 |
 Length of hospital stay (day) | 4 [4, 5] | 5 [4, 6] | 0 [− 1, 0] | – | 0.075 |
Postoperative data that may affect primary outcome | |||||
 ICU admission [n (%)] | 9 (14.5) | 8 (13.1) | 1.4 (− 10.8, 13.6) | 1.11 (0.46, 2.68) | 1.000 |
 Postoperative opioids [n (%)] | 5 (8.1) | 11 (18.0) |  − 10.0 (− 21.8, 1.8) | 0.45 (0.17, 1.21) | 0.115 |
 Hemoglobin (g L−1) | 108 [100, 115] | 107 [96, 115] | 2 (− 3, 7) | – | 0.275 |