Table 1 Baseline demographic and clinical characteristics

Age (years)

25.0 (6.90)

26.6 (7.96)

0.216^a

Gender

0.561^b

 Male

24 (40.0%)

22 (34.9%)

 Female

36 (60.0%)

41 (65.1%)

Education

0.827^b

 Junior high and below

5 (8.3%)

7 (11.1%)

 Senior high and vocational

18 (30.0%)

20 (31.7%)

 Bachelor and above

37 (61.7%)

36 (57.1%)

BMI

21.2 (3.75)

21.2 (3.03)

0.962^a

Marital status

0.669^b

 Married

49 (81.7%)

48 (76.2%)

 Single

9 (15.0%)

11 (17.5%)

 Divorced or widowed

2 (3.3%)

4 (6.3%)

Number of episodes

0.354^b

 1

27 (45.0%)

28 (44.4%)

 2

15 (25.0%)

22 (34.9%)

 3

18 (30.0%)

13 (20.6%)

 > 3

27 (45.0%)

28 (44.4%)

Overall course of disease (month)

7 (12, 45)

6 (10, 24)

0.063^c

Antidepressant

0.715^b

 SSRIs

44 (73.3%)

48 (76.2%)

 SNRIs

16 (26.7%)

15 (23.8%)

Baseline HAMD-17

19.9 (3.9)

20.9 (4.9)

0.204^a

Baseline HAMA

17.4 (5.9)

17.7 (5.5)

0.798^a

Baseline PHQ-9

15.8 (4.8)

16.1 (4.9)

0.695^a

Baseline GAD-7

9.8 (4.6)

8.5 (4.9)

0.154^a

Baseline CGI-S

4.8 (0.7)

4.6 (0.8)

0.463^a

Baseline SHAPS

34.8 (6.8)

36.5 (5.9)

0.127^a

Baseline AIS

12.0 (4.3)

12.7 (3.9)

0.398^a

Baseline SDS

6.7 (2.4)

6.8 (2.1)

0.795^a

Executive function

 DSB

6.3 (2.2)

6.4(1.9)

0.625^a

 Stroop Color-Word

42.8 (16.9)

47.2 (14.6)

0.154^a

 TMT-B

63.3 (21.4)

58.2 (24.3)

0.276^a

 DSST

63.5 (14.1)

60.5 (15.1)

0.301^a

Attention

 DSF

8.6 (1.7)

8.9 (1.7)

0.303^a

 Stroop-Word

90.4 (19.2)

90.1 (18.9)

0.930^a

Processing speed

 TMT-A

26.0 (7.2)

28.5 (9.0)

0.125^a

 Stroop-Color

76.1 (20.7)

75.8 (18.9)

0.935^a

Memory

 HVLT-R

26.8 (4.8)

25.5 (5.3)

0.209^a

 HVLT-delayed recall trial

9.5 (2.1)

9.3 (3.4)

0.845^a