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Table 4 Hazard ratios for incidence of diastolic dysfunction by CAC score among participants without dysfunction at baseline

From: Impact of coronary artery calcium on progression of diastolic dysfunction: a cohort study

 

Number of events (incidents % per year)

Adjusted hazard ratio (95% CI)a

p value

Definite DD (N = 5540)

240 (0.95)

  

 CAC = 0

62 (0.48)

Reference

 

 0 < CAC < 100

77 (0.95)

1.32 (0.90, 1.95)

0.125

 CAC ≥ 100

101 (2.34)

1.95 (1.16, 3.26)

 < 0.01

Definite or probable DD (N = 4703)

606 (2.72)

  

 CAC = 0

217 (1.82)

Reference

 

 0 < CAC < 100

218 (3.08)

1.17 (0.96, 1.44)

0.103

 CAC ≥ 100

171 (5.23)

1.46 (1.13, 1.88)

 < 0.01

  1. The hazard ratio was estimated using inverse probability weighting (see text for details) for generalizability
  2. Abbreviations: BMI Body mass index, CAC Coronary artery calcium, CI Confidence interval, DD Diastolic dysfunction
  3. aAdjusted for age, sex, BMI, smoking status (never, ever, or missing), drinking status, diabetes, hypertension, hyperlipidemia, atrial fibrillation, history of cancer, aspirin use, and statin use at baseline
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BMC Medicine

ISSN: 1741-7015

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