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Fig. 3 | BMC Medicine

Fig. 3

From: Elevated CD10− neutrophils correlate with non-response and poor prognosis of CD19 CAR T-cell therapy for B-cell acute lymphoblastic leukemia

Fig. 3

Correlation of CD10− neuts levels with non-response to CD19 CAR T-cell therapy. A–C The proportion of CD10− neuts/neutrophils, CD10− neuts/nucleated cells, and the absolute count of CD10− neuts were higher in the NR group (n = 8) compared to the CR/CRi group (n = 36). D–F ROC curve analysis for predicting clinical response using CD10− neuts/neutrophils, CD10− neuts/nucleated cells, and the absolute count of CD10− neuts. G Univariate and multivariate logistic regression analysis of independent factors influencing clinical response based on clinical and laboratory indicators. The cutoff values for age, WBC, neutrophils, and lymphocytes were set at the median. CR/CRi, complete remission or complete remission with incomplete hematological recovery; NR, non-response; OR, odds ratio; 95% CI, 95% confidence interval; WBC, white blood cell

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BMC Medicine

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