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Table 1 Baseline characteristics

From: Therapeutic hypothermia in patients with acute myocardial infarction complicated by out-of-hospital cardiac arrest

 

Total

(N = 2925)

Hypothermia

(N = 624)

No hypothermia

(N = 2301)

P value

Demographics

 Age, years

62.1 ± 12.2

60.7 ± 11.9

62.6 ± 12.3

 < 0.001

 < 50

442 (15.1)

109 (17.5)

333 (14.5)

 

 50 ~ 70

1673 (57.2)

369 (59.1)

1304 (56.7)

 

 ≥ 70

810 (27.7)

146 (23.4)

664 (28.9)

 

 Male

2533 (86.6)

560 (89.7)

1973 (85.7)

0.011

Comorbidities

 Hypertension

1321 (45.2)

273 (43.8)

1048 (45.5)

0.451

 Diabetes mellitus

849 (29.0)

165 (26.4)

684 (29.7)

0.120

 Cardiovascular disease

659 (22.5)

120 (19.2)

539 (23.4)

0.030

 Ischemic heart disease

561 (19.2)

100 (16.0)

461 (20.0)

0.028

 Valvular heart disease

13 (0.4)

1 (0.2)

12 (0.5)

0.388

 Arrhythmia

95 (3.2)

17 (2.7)

78 (3.4)

0.481

 Heart failure

66 (2.3)

13 (2.1)

53 (2.3)

0.860

 Cerebrovascular disease

227 (7.8)

40 (6.4)

187 (8.1)

0.181

 Chronic kidney disease

164 (5.6)

26 (4.2)

138 (6.0)

0.096

 Chronic lung disease

91 (3.1)

19 (3.0)

72 (3.1)

1.000

Characteristics of the cardiac arrest

 Place at cardiac arrest

   

0.971

 Public place

996 (34.1)

215 (34.5)

781 (33.9)

 

 Non-public place

1312 (44.9)

278 (44.6)

1034 (44.9)

 

 Unknown

617 (21.1)

131 (21.0)

486 (21.1)

 

 Witness type

   

0.009

Healthcare professional

478 (16.3)

79 (12.7)

399 (17.3)

 

Bystander

1745 (59.7)

400 (64.1)

1345 (58.5)

 

Unknown

702 (24.0)

145 (23.2)

557 (24.2)

 

 Layperson witnessed

2298 (78.6)

1800 (78.2)

498 (79.8)

0.425

 Bystander-performed CPR

1505 (51.5)

1172 (50.9)

333 (53.4)

0.302

 Telemetric advice before EMS

2001 (68.4)

1565 (68.0)

436 (69.9)

0.403

 Initial EMS rhythm

   

0.001

Shockable rhythm

2155 (73.7)

495 (79.3)

1660 (72.1)

 

Nonshockable rhythm

726 (24.8)

123 (19.7)

603 (26.2)

 

Unknown

44 (1.5)

6 (1.0)

38 (1.7)

 

AED use

2270 (77.6)

520 (83.3)

1750 (76.1)

 < 0.001

Arres to admission timeline

 Arrest-to-call time, min

0 (0–2)

0 (0–2)

0 (0–2)

0.235

 Call-to-door time, min

30 (24–38)

31 (26–38)

30 (24–38)

0.005

 Arrest-to-door time, min

30 (24–38)

31 (26–38)

30 (24–38)

0.005

PCI timeline

 Door-to-PCI time, min

100 (74–146)

100 (74–140)

100 (74–148)

0.492

 Procedure time, min

25 (15–41)

23 (14–40)

25 (15–41)

0.275

Characteristics on ER admission

 Initial ECG rhythm

   

0.344

Post ROSC rhythm

1450 (49.6)

310 (49.7)

1140 (49.5)

 

Shockable rhythm

335 (11.5)

81 (13.0)

254 (11.0)

 

Nonshockable rhythm

859 (29.4)

182 (29.2)

677 (29.4)

 

No record

281 (9.6)

51 (8.2)

230 (10.0)

 

 Defibrillation at ER

968 (33.1)

213 (34.1)

755 (32.8)

0.565

 Total CPR time at ER, min

4 (0–19)

4 (0–18)

4 (0–19)

0.441

 ROSC before ER admission

1321 (45.2)

281 (45.0)

1040 (45.2)

0.977

Therapeutic interventions

 ECMO

612 (20.9)

136 (21.8)

476 (20.7)

0.584

  1. Values are mean ± SD, n (%) or median (interquartile range)
  2. AED Automated external defibrillator, CPR Cardiopulmonary resuscitation, ECG Electrocardiogram, ECMO Extracorporeal membrane oxygenation, EMS Emergency medical service, ER Emergency room, PCI Percutaneous coronary intervention, ROSC Return of spontaneous circulation