Therapeutic hypothermia in patients with acute myocardial infarction complicated by out-of-hospital cardiac arrest

Table 2 Comparison of in-hospital clinical outcomes

	Hypothermia (N=624)	No hypothermia (N=2301)	Unadjusted		Multivariable-adjusted^*		IPTW-adjusted
	Hypothermia (N=624)	No hypothermia (N=2301)	OR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Mortality outcomes
Death within discharge	219 (35.1)	997 (43.3)	0.71 (0.59–0.85)	<0.001	0.72 (0.57–0.91)	0.005	0.78 (0.70–0.87)	<0.001
Death within 24 h	45 (7.2)	533 (23.2)	0.26 (0.19–0.35)	<0.001	0.24 (0.17–0.34)	<0.001	0.33 (0.28–0.38)	<0.001
Neurologic outcomes
Poor outcome (CPC 3, 4, 5)	356 (57.1)	1,339 (58.2)	0.95 (0.80–1.14)	0.609	1.06 (0.84–1.33)	0.637	1.01 (0.91–1.13)	0.824

^*Adjusted variable: age, sex, location at cardiac arrest, bystander-witnessed, bystander-performed CPR, telemetric advice to first aid before EMS, initial EMS rhythm, defibrillation before ER admission, ROSC before ER admission, initial ECG rhythm, defibrillation, total CPR time, defibrillation at ER, ECMO, and hospital region
Values are n (%, cumulative incidence) unless otherwise indicated

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