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Table 2 Standard incidence ratios for all cancers combined for the UK Biobank participants

From: Cancer incidence inconsistency between UK Biobank participants and the population: a prospective cohort study

 

Observed number of cancers

Expected number of cancers

SIR (95% CI)

P*

Overall

47,535

52,840.0

0.90 (0.89, 0.91)

 

By sex

   

1.8 × 10−34

 Females

22,029

25,970.4

0.85 (0.84, 0.86)

 

 Males

25,506

26,869.6

0.95 (0.94, 0.96)

 

By age group

 <45 years

1783

1964.6

0.91 (0.87, 0.95)

7.9 × 10−10

 45–49 years

3165

3652.1

0.87 (0.84, 0.90)

 

 50–54 years

5039

5974.6

0.84 (0.82, 0.87)

 

 55–59 years

8441

9750.8

0.87 (0.85, 0.88)

 

 60–64 years

14,775

16,182.0

0.91 (0.90, 0.93)

 

 ≥65 years

14,332

15,315.8

0.94 (0.92, 0.95)

 

By index of multiple deprivation

 First quartile (<−3.64)

11,977

13,838.5

0.87 (0.85, 0.88)

9.1 × 10−21

 Second quartile (−3.64 to −2.12)

12,026

13,642.4

0.88 (0.87, 0.90)

 

 Third quartile (−2.13, 0.551)

11,571

13,026.4

0.89 (0.87, 0.90)

 

 Fourth quartile (0.552, 11)

11,920

12,277.3

0.97 (0.95, 0.99)

 

By average total household income

 <£18,000

11,089

11,409.7

0.97 (0.95, 0.99)

2.9 × 10−21

 £18,000–£30,999

11,117

12,305.7

0.90 (0.89, 0.92)

 

 £31,000–£51,999

9493

10,891.8

0.87 (0.85, 0.89)

 

 ≥£52,000

8158

9558.5

0.85 (0.84, 0.87)

 
  1. *Linear trend test P values for subgroup analyses by age, deprivation and household income