Diagnosis of celiac disease on a gluten-free diet: a multicenter prospective quasi-experimental clinical study

Table 1 Characteristics of the participants in the study

	Celiac disease N = 20	SGRS N = 6	Healthy controls N = 9	Uncertain diagnosis N = 41
Age at inclusion (years)
Mean ± SE	40.4 ± 3.2	42.8 ± 3.7	34.1 ± 4.1	41.1 ± 1.8
Range	20–74	32–53	24–63	19–70
Age at diagnosis (years)
Mean ± SE	36.5 ± 3.5	40.0 ± 4.1	–	–
Range	11–70	27–52
Time on a GFD
Mean ± SE (months)	40.7 ± 7.7	28.7 ± 12.3	1.0 ± 0	25.7 ± 7.6^a
Range	2 months to 12 years	2 months to 6 years		1 month to 14 years
Females (N (%))	13 (65)	6 (100)	5 (56)
HLA (N)
DQ2.5	19	3	3	27
DQ8	0	2	2	4
DQ2.2	0	0	1	5
DQ7.5	1	0	1	4
Non-risk	0	1	2	1
Serology ATG2 (N)^b
ND	0	0	0	18
Positive	20	0	0	8^c
Negative	0	6	9	15
Histology (N)^b
ND	0	2	9	17
Marsh 0	0	3	0	7
Marsh 1	4	1	0	10
Marsh 2	0	0	0	0
Marsh 3	16	0	0	7

In the group of extended GC, one HLA data is missing, corresponding to “compatible” genetics with no additional information
ATG2, anti-transglutaminase type 2 antibodies; GC, gluten challenge; GFD, gluten-free diet; ND, not done; SGRS, suspected gluten-related functional bowel disease symptoms
^aFour missing data. ^bAt onset. ^cFour patients with negative anti-endomisial antibodies

ISSN: 1741-7015