Table 2 Relationships between gene expression and length of hospital stay (LOHS), length of ICU stay (LOICU) and mortality in patients with chronic P. aeruginosa lung infection (n = 70) based on the hazard ratio (HR) as standardised (Z score) adjusted for sex and age. P < 0.05 was considered to indicate significance

HR (95% CI) P

HR (95% CI) P

HR (95% CI) P

Gene expression

tesG

0.13 (0.07, 0.23) 0.0010

0.15 (0.074, 0.29) 0.0010

1.29 (0.21, 7.92) 0.786

lasR

0.36 (0.26, 0.51) 0.0010

0.44 (0.29, 0.67) 0.0010

1.11 (0.27, 4.49) 0.884

rhlA

0.35 (0.25, 0.49) 0.0010

0.43 (0.29, 0.65) 0.0010

0.96 (0.25, 3.67) 0.955

lasB

0.32 (0.23, 0.46) 0.0010

0.34 (0.21, 0.55) 0.0010

0.79 (0.27, 2.39) 0.685

lasA

0.5 (0.38, 0.66) 0.0010

0.54 (0.37, 0.79) 0.0010

0.94 (0.48, 1.83) 0.850

sagS

0.49 (0.35, 0.69) 0.0010

0.54 (0.33, 0.88) 0.013

0.18 (0.06, 0.44) 0.0010

rsmY

0.66 (0.50, 0.86) 0.002

0.81 (0.58, 1.14) 0.224

1.54 (0.84, 2.82) 0.165

rsmZ

0.59 (0.44, 0.79) 0.0010

0.77 (0.53, 1.09) 0.145

1.42 (0.79, 2.56) 0.238

pelB

0.29 (0.19, 0.43) 0.0010

0.27 (0.16, 0.45) 0.0010

0.82 (0.25, 2.70) 0.745

phzF

0.23 (0.15, 0.36) 0.0010

0.28 (0.16, 0.47) 0.0010

1.61 (0.45, 5.8) 0.462

algD

0.31 (0.21, 0.47) 0.0010

0.34 (0.21, 0.56) 0.0010

1.11 (0.63, 1.969) 0.701