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Table 1 Descriptive statistics of participants by cardiovascular health defined by Life’s Essential 8 score

From: Association of Life’s Essential 8 with incidence of heart failure modified by depressive symptoms: a prospective cohort study from UK Biobank

Characteristics

Overall (N = 336,939)

Cardiovascular health defined by LE8 scorea

P value

Low (N = 30,257)

Moderate (N = 269,488)

High (N = 37,194)

Age

56.1 (8.1)

56.9 (7.6)

56.5 (8.0)

52.1 (8.1)

 < 0.001

Male, n (%)

151,941 (45.1)

15,429 (51.0)

125,591 (46.6)

10,921 (29.4)

 < 0.001

College or university degree, n (%)

116,950 (34.7)

6818 (22.5)

92,042 (34.2)

18,090 (48.6)

 < 0.001

White, n (%)

322,620 (95.8)

28,837 (95.3)

258,104 (95.8)

35,679 (95.9)

 < 0.001

Townsend Deprivation Indexb

 − 2.3 (− 3.7, 0.2)

 − 1.5 (− 3.3, 1.6)

 − 2.3 (− 3.7, 0.1)

 − 2.4 (− 3.8, − 0.2)

 < 0.001

Alcohol consumed daily or almost daily, n (%)

70,948 (21.1)

6516 (21.5)

58,271 (21.6)

6161 (16.6)

 < 0.001

Sedentary behavior time, hours/day

4.8 (2.4)

5.7 (2.9)

4.8 (2.3)

3.9 (2.0)

 < 0.001

Healthy diet score (0–10)b

3 (2, 4)

3 (2, 3)

3 (2, 4)

4 (3, 5)

 < 0.001

Moderate activityb, min/week

120 (30, 300)

0 (0, 60)

120 (40, 300)

180 (90, 360)

 < 0.001

Vigorous activityb, min/week

30 (0, 120)

0 (0, 0)

30 (0, 120)

90 (30, 180)

 < 0.001

Current smokers, n (%)

33,787 (10.0)

10,349 (34.2)

23,284 (8.6)

154 (0.4)

 < 0.001

Secondary smoking exposure, n (%)

30,912 (9.9)

4120 (18.5)

24,847 (9.8)

1945 (5.2)

 < 0.001

Sleep duration (7–9 h), n (%)

232,632 (69.0)

13,670 (45.2)

187,331 (69.5)

31,631 (85.0)

 < 0.001

BMI, kg/m2

27.2 (4.6)

32.0 (5.6)

27.2 (4.2)

23.3 (2.5)

 < 0.001

SBP, mm Hg

137.9 (18.5)

147.9 (17.6)

139.2 (17.9)

120.6 (12.3)

 < 0.001

DBP, mm Hg

82.7 (10.1)

88.8 (9.7)

83.2 (9.6)

73.6 (7.5)

 < 0.001

Total cholesterol, mg/dL

223.1 (42.8)

239.3 (46.8)

225.0 (42.1)

196.4 (32.4)

 < 0.001

HDL cholesterol, mg/dL

56.7 (14.7)

50.3 (12.5)

56.6 (14.6)

62.4 (14.7)

 < 0.001

Non-HDL cholesterol, mg/dL

166.5 (40.8)

188.9 (43.5)

168.4 (39.3)

134.0 (28.5)

 < 0.001

Glucose, mg/dL

91.4 (20.4)

100.2 (36.9)

91.1 (18.3)

86.4 (12.2)

 < 0.001

HbA1c, %

5.4 (0.6)

5.8 (0.9)

5.4 (0.5)

5.2 (0.3)

 < 0.001

Prevalent hypertension, n (%)

125,976 (37.4)

19,435 (64.2)

103,903 (38.6)

2638 (7.1)

 < 0.001

Prevalent diabetes, n (%)

14,538 (4.3)

3626 (12.0)

10,614 (3.9)

298 (0.8)

 < 0.001

Prevalent cancer, n (%)

29,850 (8.9)

2910 (9.6)

24,042 (8.9)

2898 (7.8)

 < 0.001

Prevalent depressive symptoms, n (%)

38,592 (11.5)

5490 (18.1)

29,610 (11.0)

3492 (9.4)

 < 0.001

LE8 scoresb

 Total LE8 score

66.2 (58.1, 73.8)

45.0 (41.3, 47.5)

66.3 (60.0, 71.9)

83.8 (81.3, 86.3)

 < 0.001

 Behavior subscale score

81.3 (71.3, 87.5)

45.0 (36.3, 53.8)

71.3 (60.0, 80.0)

81.3 (77.5, 87.5)

 < 0.001

 Biological subscale score

62.5 (52.5, 73.8)

42.5 (35.0, 50.0)

61.3 (53.8, 71.3)

87.5 (81.3, 92.5)

 < 0.001

 Diet score

25 (25, 50)

25 (25, 25)

25 (25, 50)

50 (25, 50)

 < 0.001

 Physical activity score

100 (40, 100)

0 (0, 40)

100 (60, 100)

100 (100, 100)

 < 0.001

 Tobacco/nicotine exposure score

100 (55, 100)

50 (0, 80)

100 (55, 100)

100 (100, 100)

 < 0.001

 Sleep health score

100 (70, 100)

90 (70, 100)

100 (90, 100)

100 (100, 100)

 < 0.001

 BMI score

100 (70, 100)

30 (30, 70)

70 (70, 100)

100 (100, 100)

 < 0.001

 Blood lipids score

40 (20, 60)

20 (0, 40)

40 (20, 60)

80 (60, 100)

 < 0.001

 Blood pressure score

50 (25, 70)

25 (0, 30)

30 (25, 50)

100 (50, 100)

 < 0.001

 Blood glucose score

100 (100, 100)

100 (60, 100)

100 (100, 100)

100 (100, 100)

 < 0.001

  1. Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; SBP, systolic blood pressure; HDL, high-density lipoprotein; LE8, Life’s Essential 8; IQR, interquartile range; SD, standard deviation
  2. aContinuous variables are presented as mean (SD); categorical variables are presented as N (%)
  3. bThose characteristics were presented as median (IQR)