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Table 2 The associations of early-life risk score with T2D in adulthood

From: Longitudinal association of cumulative risk factors in early life, genetic risk, and healthy lifestyles during adulthood with the risk of type 2 diabetes

T2D

Early-life risk score, HR (95% CI)

P-trend

0

1

2

3

Model 1

Ref (1.0)

1.14 (1.08, 1.20)

1.25 (1.16, 1.34)

1.85 (1.58, 2.16)

<0.001

Model 2

Ref (1.0)

1.15 (1.09, 1.21)

1.28 (1.19, 1.37)

1.97 (1.68, 2.30)

<0.001

Model 3

Ref (1.0)

1.15 (1.10, 1.21)

1.26 (1.17, 1.36)

1.90 (1.63, 2.22)

<0.001

Model 4

Ref (1.0)

1.16 (1.10, 1.22)

1.26 (1.17, 1.36)

1.93 (1.65, 2.26)

<0.001

  1. Abbreviation: HR Hazard ratio, CI Confidence interval, T2D Type 2 diabetes. Model 1: crude model; Model 2: adjusted for sex; Model 3: adjusted for Model 2+age, Townsend Deprivation Index, birth year, ethnicity, household income, education, region; Model 4: Model 3+family history of diabetes
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BMC Medicine

ISSN: 1741-7015

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