Table 2 Most common TRAEsa
AE | Grade 1–2 (%) | Grade 3 (%) | Total patients, no. (%) |
|---|---|---|---|
Thrombocytopenia | 14 (45.2) | 1 (3.2) | 15 (48.4) |
Hypertension | 5 (16.1) | 9 (29.0) | 14 (45.2) |
Leucopenia | 10 (32.3) | 3 (9.7) | 13 (41.9) |
Neutropenia | 10 (32.3) | 3 (9.7) | 13 (41.9) |
Diarrhea | 8 (25.8) | 1 (3.2) | 9 (29.0) |
Proteinuria | 7 (22.6) | 2 (6.5) | 9 (29.0) |
Serum creatinine increased | 8 (25.8) | 0 (0) | 8 (25.8) |
Weight loss | 7 (22.6) | 1 (3.2) | 8 (25.8) |
Fatigue | 6 (19.4) | 1 (3.2) | 7 (22.6) |
Hypertriglyceridemia | 7 (22.6) | 0 (0) | 7 (22.6) |
Hand-foot syndrome | 6 (19.4) | 0 (0) | 6 (19.4) |
Oral mucositis | 6 (19.4) | 0 (0) | 6 (19.4) |
Hyperuricemia | 5 (16.1) | 0 (0) | 5 (16.1) |
Hypothyroidism | 5 (16.1) | 0 (0) | 5 (16.1) |
Hypercholesterolemia | 4 (12.9) | 0 (0) | 4 (12.9) |
Decreased appetite | 4 (12.9) | 0 (0) | 4 (12.9) |
Rash | 3 (9.7) | 1 (3.2) | 4 (12.9) |