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Table 1 Characteristics of participants in ChinaHEART study with different BP group using 2023 ESH guideline

From: Association of high-normal blood pressure defined by the 2023 European Society of Hypertension guideline with mortality in the Chinese population: a nationwide, population-based, prospective study of 3.6 million adults

Characteristics

Overall (N = 3,598,940)

Optimal (N = 652,400)

Normal (N = 700,948)

High-normal (N = 674,509)

Hypertension (N = 1,571,083)

SBP/DBP, mmHg

 

 < 120 and < 80

120–129 and 80–84

130–139 and/or 85–89

 > = 140 and/or > = 90

SBP, mm Hg, mean (SD)

136.55 (20.2)

111.19 (6.2)

123.56 (4.2)

132.83 (4.8)

148.83 (10.8)

DBP, mm Hg, mean (SD)

81.92 (10.8)

70.79 (4.9)

76.63 (5.4)

80.63 (6.2)

90.82 (5.6)

Men, n (%)

1,442,720 (40.1)

214,622 (32.9)

284,940 (40.7)

288,039 (42.7)

655,119 (41.7)

Age, year, mean (SD)

56.00 (10.0)

51.16 (9.7)

53.59 (9.9)

55.80 (9.8)

57.38 (8.7)

Age, year, n (%)

 35–44

531,287 (14.8)

186,093 (28.5)

144,495 (20.6)

95,230 (14.1)

105,469 (6.7)

 45–54

1,099,905 (30.6)

243,356 (37.3)

246,450 (35.2)

217,567 (32.3)

392,532 (25.0)

 55–64

1,107,540 (30.8)

147,852 (22.7)

190,746 (27.2)

210,786 (31.3)

558,156 (35.5)

 65–75

860,208 (23.9)

75,099 (11.5)

119,257 (17.0)

150,926 (22.4)

514,926 (32.8)

Region, n (%)

 East China

1,122,218 (31.2)

184,790 (28.3)

209,409 (29.9)

213,021 (31.6)

514,998 (32.8)

 Central China

840,327 (23.3)

139,422 (21.4)

154,991 (22.1)

157,425 (23.3)

388,489 (24.7)

 West China

1,307,488 (36.3)

277,967 (42.6)

262,227 (37.4)

234,400 (34.8)

532,894 (33.9)

 Northeast China

328,907 (9.1)

50,221 (7.7)

74,321 (10.6)

69,663 (10.3)

134,702 (8.6)

Education, n (%)

 Primary school and below

1,641,299 (45.6)

239,953 (36.8)

286,765 (40.9)

307,999 (45.7)

806,582 (51.3)

 Middle school

1,148,403 (31.9)

216,840 (33.2)

234,510 (33.5)

222,205 (32.9)

474,848 (30.2)

 High school and above

771,773 (21.4)

189,075 (29.0)

171,650 (24.5)

136,527 (20.2)

274,521 (17.5)

 Unknown

37,465 (1.0)

6,532 (1.0)

8,023 (1.1)

7,778 (1.2)

15,132 (1.0)

Annual household income, RMB, n (%)

 < 10 k

614,424 (17.1)

90,509 (13.9)

105,873 (15.1)

113,782 (16.9)

304,260 (19.4)

 10 k- 50 k

1982,603 (55.1)

350,826 (53.8)

387,511 (55.3)

376,771 (55.9)

867,495 (55.2)

 > = 50 k

670,264 (18.6)

148,813 (22.8)

143,041 (20.4)

121,379 (18.0)

257,031 (16.4)

 Unknown

331,649 (9.2)

62,252 (9.5)

64,523 (9.2)

62,577 (9.3)

142,297 (9.1)

 Live in Rural, n (%)

2,189,361 (60.8)

374,102 (57.3)

411,081 (58.6)

409,753 (60.7)

994,425 (63.3)

Current smoker, n (%)

700,898 (19.5)

116,578 (17.9)

133,954 (19.1)

136,179 (20.2)

314,187 (20.0)

Current drinker, n (%)

871,938 (24.2)

139,203 (21.3)

158,797 (22.7)

164,773 (24.4)

409,165 (26.0)

BMI, kg/m2, mean (SD)

24.74 (3.4)

23.41 (3.0)

24.14 (3.1)

24.66 (3.2)

25.64 (3.5)

BMI, kg/m2, n (%)

 < 18

39,086 (1.1)

13,163 (2.0)

8,348 (1.2)

6,581 (1.0)

10,994 (0.8)

 18–24

1,988,249 (55.3)

462,086 (70.9)

442,723 (63.2)

379,541 (56.3)

703,899 (44.8)

 24–28

988,731 (27.5)

130,554 (20.0)

174,255 (24.9)

189,638 (28.2)

494,284 (31.5)

 > = 28

578,626 (16.1)

45,896 (7.0)

74,637 (10.7)

97,872 (14.5)

360,221 (22.9)

Total cholesterol, mmol/L, mean (SD)

4.58 (1.1)

4.41 (1.00)

4.48 (1.01)

4.57 (1.0)

4.64 (1.08)

Total cholesterol, mmol/L, n (%)

 < 5.2

2,710,392 (75.3)

527,080 (80.8)

553,891 (79.0)

512,402 (76.0)

1,117,019 (71.1)

 5.2–6.19

640,420 (17.8)

93,632 (14.4)

109,055 (15.6)

118,901 (17.6)

318,832 (20.3)

 > = 6.2

248,128 (6.9)

31,688 (4.9)

38,002 (5.4)

43,206 (6.4)

135,232 (8.6)

HDL-cholesterol, mmol/L, mean (SD)

1.42 (0.4)

1.44 (0.4)

1.43 (0.4)

1.43 (0.4)

1.39 (0.4)

LDL-cholesterol, mmol/L, mean (SD)

2.44 (0.9)

2.34 (0.9)

2.39 (0.9)

2.45 (0.9)

2.48 (0.9)

Triglycerides, mmol/L, median (IQR)

1.58 (0.8)

1.42 (0.7)

1.50 (0.8)

1.56 (0.8)

1.7 (0.9)

Fasting blood glucose, mmol/L, mean (SD)

6.14 (1.7)

5.82 (1.4)

5.90 (1.5)

6.07 (1.6)

6.35 (1.8)

Fasting blood glucose, mmol/L, n (%)

 < 5.6

1,388,048 (38.6)

312,806 (47.9)

316,862 (45.2)

267,785 (39.7)

490,595 (31.2)

 5.6–6.9

1,620,079 (45.0)

275,923 (42.3)

303,037 (43.2)

308,761 (45.8)

732,358 (46.6)

 > = 7.0

590,813 (16.4)

63,671 (9.8)

81,049 (11.6)

97,963 (14.5)

348,130 (22.2)

Medical history, n (%)

 Cardiovascular disease

107,033 (3.0)

8,903 (1.4)

10,671 (1.5)

12,645 (1.9)

74,814 (4.8)

 Stroke

73,094 (2.0)

4,976 (0.8)

6,435 (0.9)

7,926 (1.2)

53,757 (3.4)

 Myocardial infarction

21,015 (0.6)

2,511 (0.4)

2,671 (0.4)

2,867 (0.4)

12,966 (0.8)

 Hypertension

681,103 (18.9)

0 (0.0)

0 (0.0)

0 (0.0)

681,103 (43.4)

 Diabetes mellitus

234,467 (6.5)

19,988 (3.1)

27,080 (3.9)

33,543 (5.0)

153,856 (9.8)

 Dyslipidemia, n (%)

352,489 (9.8)

41,662 (6.4)

49,993 (7.1)

56,390 (8.4)

204,444 (13.0)

 Anti-hypertensive drug use, n(%)

468,944 (13.0)

0 (0.0)

0 (0.0)

0 (0.0)

468,944 (29.8)

High CVD risk a, n (%)

819,620 (22.8)

39,681 (6.1)

45,762 (6.5)

50,530 (7.5)

683,647 (43.5)

Mortality, n (%)

 Total mortality

80,494 (2.2)

8,611 (1.3)

11,265 (1.6)

13,092 (1.9)

47,526 (3.0)

 CVD mortality

33,450 (0.9)

2,492 (0.4)

3,725 (0.5)

4,741 (0.7)

22,492 (1.4)

 Non-CVD mortality

47,044 (1.3)

6,119 (0.9)

7,540 (1.1)

8,351 (1.2)

25,034 (1.6)

  1. Abbreviations: BP Blood pressure, ESH European society of hypertension, SD Standard deviation, SBP Systolic blood pressure, DBP Diastolic blood pressure, BMI Body mass index (calculated as weight in kilograms divided by height in meters squared), HDL High-density lipoprotein, LDL Low-density lipoprotein, IQR interquartile range, CVD Cardiovascular disease
  2. SI conversion factors: To convert HDL, LDL and total cholesterol to mg/dL, divide by 0.0259; Fasting blood glucose to mg/dL, divide by 0.0555; Triglycerides to mg/dL, divide by 0.0113
  3. aHigh CVD risk should meet at least one of four criteria: (i) major cardiovascular events history (myocardial infarction, percutaneous coronary intervention, coronary artery bypass graft or stroke); (ii) a predicted CVD risk ≥ 20% based on World Health Organization(WHO)/International Society of Hypertension cardiovascular risk prediction charts [15]; (iii) severely abnormal blood lipid levels (LDL ≥ 4.14 mmol/L or HDL < 0.78 mmol/L); or (iv) severely high blood pressure (SBP > 160 mmHg or DBP > 100 mmHg)