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Table 2 Linear regression models for adjusting cognitive variables by age and sex

From: Neurocognitive resilience as a predictor of psychosis onset and functional outcomes in individuals at high risk

 

Age (years)

Sex (1 = man; 2 = woman)

Constant

 

β (S.E.)

t (p)

β (S.E.)

t (p)

β (S.E.)

t (p)

Trail Making A

 − 0.188 (0.060)

 − 3.125 (0.002)

1.631 (0.641)

2.543 (0.011)

32.692 (1.634)

20.010 (< 0.001)

BACS symbol coding

0.161 (0.053)

3.052 (0.002)

0.756 (0.562)

1.344 (0.179)

56.448 (1.433)

39.385 (< 0.001)

HVLT-R

 − 0.021 (0.023)

 − 0.921 (0.357)

0.831 (0.247)

3.368 (0.001)

24.590 (0.628)

39.137 (< 0.001)

WMS-3 spatial span

 − 0.004 (0.015)

 − 0.287 (0.774)

 − 0.945 (0.159)

 − 5.930 (< 0.001)

17.571 (0.406)

43.300 (< 0.001)

NAB mazes

 − 0.069 (0.026)

 − 2.637 (0.008)

 − 2.083 (0.280)

 − 7.430 (< 0.001)

22.994 (0.714)

32.202 (< 0.001)

BVMT-R

 − 0.078 (0.029)

 − 2.709 (0.007)

1.013 (0.305)

3.322 (0.001)

27.339 (0.777)

35.188 (< 0.001)

Category Fluency

0.159 (0.028)

5.609 (< 0.001)

 − 0.129 (0.302)

 − 0.428 (0.668)

18.876 (0.769)

24.547 (< 0.001)

CPT-IP

0.034 (0.004)

9.563 (< 0.001)

 − 0.025 (0.038)

 − 0.659 (0.510)

2.012 (0.097)

20.721 (< 0.001)

  1. Adjusted Cognitive Score = Original Cognitive Score − (Age × (β) + Sex × (β) + Constant)
  2. β Denotes the regression coefficient, SE is the standard error. Significant statistical results are presented in bold
  3. Abbreviations: BACS Brief Assessment of Cognition in Schizophrenia symbol coding , BVMT-RBrief Visuospatial Memory Test–Revised , CPT-IPContinuous Performance Test–Identical Pairs , HVLT-RHopkins Verbal Learning Test–Revised, NABNeuropsychological Assessment Battery mazes , WMS-3Wechsler Memory Scale–Third Edition spatial span
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BMC Medicine

ISSN: 1741-7015

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