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Fig. 7 | BMC Medicine

Fig. 7

From: Integration of multi-omics data to unveil the molecular landscape and role of piRNAs in early-onset colorectal cancer

Fig. 7

Identification of downstream pathways of FR019089 and FR019019. RKO cells were treated with mimic-FR019089, -FR019019, or -negative control (n = 4 for each group). A,B Volcano plots illustrate the differentially expressed genes between mimic-negative control with -FR019089 (A) or -FR019019 (B). Upregulated genes are shown in red and downregulated genes are shown in blue. C,D Results of gene-set enrichment analysis for significant pathways related to aggressiveness of colorectal cells in mimic-FR019089 (C) and mimic-FR019019 (D) group (qvalue < 0.05)

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