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Table 3 Clinical information

From: Probiotic mitigates gut hypoperfusion-associated acute gastrointestinal injury in patients undergoing cardiopulmonary bypass: a randomized controlled trial

Variables

Total

Lac group n = 26

Placebo group n = 26

P

POD 1

 White blood cells (× 109/L), mean ± SD

12.90 ± 4.05

12.37 ± 3.67

13.42 ± 4.42

0.357

 CRP (mg/L), mean ± SD

98.52 ± 52.17

82.42 ± 45.49

114.32 ± 54.45

0.028

 IL- 6 (pg/ml), median (IQR)

197 (130.25, 343)

187 (135, 344)

391 (205, 709)

0.042

 PCT (ng/ml), median (IQR)

15.35 (4.65, 25.6)

8.66 (4.58, 18.3)

22.5 (7.98, 100)

0.071

 NT-proBNP (ng/L), median (IQR)

1245 (677.5, 2581.5)

1021 (688, 1411)

4066 (1050, 6719)

0.040

 hs-TnI (ng/ml), median (IQR)

4.82(2.07, 12.84)

3.76 (1.79, 6.01)

11.91 (3.76, 28.44)

0.004

 I-FABP 2 (ng/ml), median (IQR)

0.75 (0.25, 1.35)

0.29 (0.08, 0.73)

1.64 (0.57, 2.87)

0.010

 LVEF (%), median (IQR)

50 (43.5, 55)

50 (49, 56)

43 (24, 50)

0.001

POD 3

 White blood cells (× 109/L), mean ± SD

14.11 ± 4.42

14.41 ± 4.96

13.81 ± 3.88

0.629

 CRP (mg/L), mean ± SD

170.11 ± 57.11

153.36 ± 60.08

186.87 ± 49.58

0.033

 IL- 6 (pg/ml), median (IQR)

110 (64.28, 165)

99 (63.4, 130.6)

253 (99.5, 487.5)

0.066

 PCT (ng/ml), median (IQR)

6.6(2.75, 16.4)

5.36 (2.42, 9.33)

37.7 (5.24, 100)

0.010

 NT-proBNP (ng/L), median (IQR)

1809 (1029, 3918.5)

1092 (794.5, 2454)

3953 (2169,7001)

0.001

 hs-TnI (ng/ml), median (IQR)

2.28 (0.96, 4.71)

1.63 (0.75, 2.75)

4.72 (1.91, 24.18)

0.003

 I-FABP 2 (ng/ml), median (IQR)

0.43 (0.11, 0.84)

0.18 (0.08, 0.46)

0.87 (0.21, 3.87)

0.012

Gastrointestinal indicators

 Return time of bowel sounds (day), median (IQR)

1 (1, 2)

1 (1, 2)

3 (1, 5)

0.056

 IAP (cmH2O), median (IQR)

8 (7, 12.75)

9 (7.5, 13)

14 (9, 19)

0.042

 Number of bowel sounds

(times), median (IQR)

3 (3, 4)

3 (2.5, 4)

2 (1, 4)

0.106

 First defecation time (days), median (IQR)

3 (2, 4)

3 (2, 4)

4 (3, 6)

0.006

 Bristol Stool Form Scale score, median (IQR)

4 (4, 5)

4 (4, 5)

6 (4, 7)

0.086

 Proportion of coccus feces (%), median (IQR)

20 (20, 40)

20 (20, 50)

50 (20, 90)

0.104

  1. CRP C-reactive protein, IL- 6 interleukin- 6, AST aspartate transaminase, ALT alanine aminotransferase, γ-GGT γ-Glutamyl transferase, TBIL total bilirubin, IAP intra-abdominal pressure, I-FABP 2 intestinal-type fatty acid-binding protein 2, LVEF left ventricular ejection fractions, NT-proBNP N-Terminal pro-brain natriuretic peptide, hs-TnI high sensitive troponin I, IQR interquartile range, SD standard deviation, RBC red blood cells