Fig. 1

Flowchart of study design. The research overview summarizes the selection and analysis process of the population. Abbreviations: ADNI, Alzheimer’s Disease Neuroimaging Initiative; FAQ, Functional assessment questionnaire; MCI, Mild cognitive impairment; NC, Normal cognition; AD, Alzheimer’s diseases; MRI, Magnetic resonance imaging; PET, Positron emission tomography; CSF, Cerebral spinal fluid