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Table 1 Demographic characteristics of the participants [mean ± SD or n (%)]

From: Placental and cord serum inflammatory cytokines and children’s domain-specific neurodevelopment at 18 months: effect modification by maternal vitamin D status

Characteristics

Total (n = 1241)

Maternal and family characteristics

 Maternal age at enrollment (years)

26.63 ± 3.55

 Pre-pregnancy BMI (kg/m2)

20.59 ± 2.88

Delivery mode

 Vaginal delivery

557 (44.9)

 Cesarean section

684 (55.1)

Family monthly income per capita (CNY)

 ≤ 2500

342 (27.6)

 2500–4000

522 (42.0)

 > 4000

377 (30.4)

Smoking and drinking during pregnancy

 Yes

112 (9.0)

 No

1129 (91.0)

Maternal fever during pregnancy

 Yes

153 (12.3)

 No

1088 (87.7)

Maternal infection or inflammation conditions during pregnancy

 Yes

100 (8.1)

 No

1141 (91.9)

Maternal pregnancy-related anxiety

 Yes

588 (47.4)

 No

653 (52.6)

Maternal folic acid supplementation during pregnancy

 Yes

1132 (91.2)

 No

109 (8.8)

Average concentrations of maternal serum 25(OH)D during pregnancy

19.60 ± 6.05

 < 20 ng/mL

728 (58.7)

 ≥ 20 ng/mL

513 (41.3)

Placental characteristics

Placental weight (g)

571.96 ± 162.77

Placental efficiency

6.39 ± 2.87

Children’s characteristics

 Birth weight (g)

3382.68 ± 429.32

 Gestational age (weeks)

39.14 ± 1.27

 Children’s age at neurodevelopmental testing (months)

18.16 ± 0.60

Sex

 Boys

629 (50.7)

 Girls

612 (49.3)

Main caregivers

 Parents

246 (19.8)

 Parents and grandparents

908 (73.2)

 Others

87 (7.0)

Breastfeeding duration (months)

 < 1

363 (29.3)

 1–4

173 (13.9)

 > 4

705 (56.8)

  1. SD Standard deviation, BMI Body mass index, CNY Chinese yuan