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Table 1 Baseline demographics and disease characteristics of participants (n = 52)

From: Nimotuzumab combined with docetaxel and cisplatin as first-line treatment for patients with recurrent or metastatic nasopharyngeal carcinoma: a multicenter, phase 2 trial

Characteristic

Patients

Age, years

 Median

44

 Range

25–63

Gender, n (%)

 Male

41 (78.8)

 Female

11 (21.2)

ECOG performance score, n (%)

 0

49 (94.2)

 1

3 (5.8)

Smoking status, n (%)

 Yes

13 (25.0)

 No

39 (75.0)

Disease status, n (%)

 Primary metastatic

29 (55.8)

 Recurrent

23 (44.2)

Histology, n (%)

 Non-keratinizing undifferentiated

51 (98.1)

 Poorly differentiated

1 (1.9)

Lung metastases, n (%)

 Yes

15 (28.8)

 No

37 (71.2)

Liver metastases, n (%)

 Yes

23 (44.2)

 No

29 (55.8)

Bone metastases, n (%)

 Yes

23 (44.2)

 No

29 (55.8)

Expression of EGFR, n (%)

 Negative

2 (3.8)

 Weak staining

37 (71.2)

 Intermediate staining

1 (1.9)

 Strong staining

7 (13.5)

 Unknown

5 (9.6)

Baseline EBV DNA level, copies/mL

 Median

8965

 Interquartile range

1965-57,625

 ≥ 10,000

25 (48.1)

 < 10,000

27 (51.9)

  1. Data are shown as number (%) unless otherwise specified
  2. Abbreviations: ECOG Eastern Cooperative Oncology Group, EBV Epstein-Barr virus, EGFR Epidermal growth factor receptor